UW Biotechnology Center Auditorium @ 12:00 pm - 1:00 pm
Title: Beyond Gene Dosage: Multidimensional Islet Dysfunction in Down Syndrome-Related Type 2 Diabetes Abstract: Individuals with Down syndrome are four times more likely to develop type 2 diabetes (T2D) than the general population, with onset occurring …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
Title: Environmental Regulation of Intestinal Epithelial Function: Insights from Organoid Models Abstract: The intestinal epithelium is continuously exposed to environmental signals derived from the microbiota, immune system, and host metabolic pathways. These signals influence epithelial renewal, …
DeLuca Forum in the Discovery Building @ 12:00 pm - 1:00 pm
Title: Towards Bioengineering Scalable Models of Human Central Nervous System Development and Disease Abstract: Recent years have brought about a rapid acceleration in the adoption of human-based ‘new approach methodologies’ (NAMs) in drug discovery, toxicity testing, …
DeLuca Forum in the Discovery Building @ 12:00 pm - 1:00 pm
Title: Species-specific developmental clock models derived from pluripotent stem cells Abstract: Biological clocks are fundamental to life, coordinating cellular processes over time to ensure orderly development and tissue formation. The segmentation clock is one of the …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
Title: Targeting inflammatory salivary gland dysfunction: the therapeutic potential of MSCs Abstract: This talk will review mesenchymal stromal cells (MSCs) and their functional properties, how one might approach optimizing therapeutic MSCs, and update the group on …
DeLuca Forum in the Discovery Building @ 12:00 pm - 1:00 pm
Title: Multi-omic and predictive modeling approaches to engineer robust human pluripotent stem cell differentiation to cardiomyocytes Abstract: Cardiovascular disease, specifically ischemic heart disease, has been the global leading cause of death for over a century. …
DeLuca Forum in the Discovery Building @ 12:00 pm - 1:00 pm
Title: Mitochondrial Contributions to Hematopoietic Homeostasis and the Pathogenesis of Hematological Disorders Abstract: Hematopoietic stem cells (HSCs) rely on precisely coordinated metabolic programs to preserve their function, adapt to environmental cues, and sustain lifelong hematopoiesis. …
UW Biotechnology Center Auditorium @ 12:00 pm - 1:00 pm
Title: Spatial resolution of extraendocrine Slit2/3 in compensatory islet expansion Abstract: Pancreatic islets are endocrine cell clusters that regulate blood glucose homeostasis through the secretion of hormones such as insulin, glucagon, and somatostatin. While islet …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
Title: Engineering vascularized tissues to study cell-cell communication Abstract: My lab is interested in building vascularized human tissue models, in order to study how cell-cell communication influences development, regeneration, and disease. In this talk, I will …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
Title: Progress in Human Pluripotent Stem Cell-based Therapies for Cardiac Regeneration Join Zoom Meeting https://uwmadison.zoom.us/j/91814162149?pwd=AYgwgbFNekOLHyQrj7wUCkxem9b2Yw.1 Meeting ID: 918 1416 2149 Passcode: 970506