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SCRMC Updates

  • Novel approach promises ready access to hard-to-study proteins

    SCRMC faculty member Ying Ge reports the development of a novel strategy capable of extracting and driving hard-to-reach proteins into water solution where they can be effectively studied using mass spectrometry, a powerful analytical technique.  The new …

  • Secondary insult reveals etiology of GATA2 enhancer mutation-associated blood disorder

    The transcription factor GATA-2 is critical regulator of hematopoietic stem and progenitor cell (HSPC) development and function, and mutations in the enhancer region of GATA2 are linked to blood disorders. In this episode, Emery Bresnick and colleagues develop and characterize a mouse model that harbors a human disease-associated GATA2 enhancer mutation. In this model, hematopoietic development and function were normal unless the animals were exposed to a secondary stress that necessitated blood cell regeneration. The results of this study provide important insight into GATA-2-dependent pathogenesis.

  • Four faculty receive 2019 Hilldale Awards

    SCRMC faculty member, Linda Schuler, was a member of the first class of professors hired to inaugurate the UW–Madison School of Veterinary Medicine in 1983. Her research defined the genetic details of the hormonal control of milk production in dairy cows. That work led Schuler to discover that the milk-stimulating hormone prolactin can induce breast cancer, distinguishing her as a researcher eager to pursue leads toward the next problem.

  • UW program for advanced cell therapy launches first clinical trial

    The UW Program for Advanced Cell Therapy (PACT) will conduct a study to examine a cutting-edge therapy to treat a viral infection faced by up to 50 percent of bone-marrow transplant recipients.

  • Video: Stem cells, lab to clinic

    Forward Bio Institute director Bill Murphy and David Gamm, director of the McPherson Eye Research Institute, where stem cells are being turned into retinal cells to try to find cures for blinding disorders, explain how stem cell scientists are working with industry to put scientific breakthroughs on the path to helping patients.

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