Orchard View Room (Discovery Building) @ 12:00 pm - 1:00 pm
Title: Defining regulatory networks in orofacial morphogenesis and cleft lip pathogenesis Abstract: Cleft lip, one of the most common structural birth defects, results from deficient outgrowth of the medial nasal process (MNP) the forms the …
Orchard View Room (Discovery Building) @ 12:00 pm - 1:00 pm
Title: Tiny Fish, Big Insights: Danionella cerebrum as a Novel Vertebrate Model for Regeneration Research Abstract: Dr. Lam is an Associate Professor at the Medical College of Wisconsin. Her laboratory utilizes the emerging vertebrate model Danionella …
Orchard View Room (Discovery Building) @ 12:00 pm - 1:00 pm
Title: Getting the Right hPSC-derived Cardiomyocytes for the Job Abstract: Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are a promising cell source for cardiac therapies and generating models of heart disease. However, robust methods to generate …
HSLC Room 1306 @ 12:00 pm - 1:00 pm
Title: When the Patient Becomes the Model: iPSC-RPE for Disease Discovery and Therapeutic Development Abstract: Building on inherited retinal diseases caused by ion-channel defects, we developed a human-centered experimental strategy using induced pluripotent stem cells …
UW Biotechnology Center Auditorium @ 12:00 pm - 1:00 pm
Title: The Surprising Biology of Metadherin: Lessons from a Dispensable but Evolutionarily Conserved Cancer Fitness Gene Abstract: Metadherin (MTDH) exemplifies a quintessential cancer fitness gene—a gene largely dispensable during normal physiological development that play key roles …
Orchard View Room (Discovery Building) @ 12:00 pm - 1:00 pm
Title: The ISSCR Consortium: Advancing Human Stem Cell-Based Models in Drug Discovery & Development Abstract: Human stem cell-derived disease models provide a unique opportunity to accelerate drug discovery and development through more predictive preclinical models. However, …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
Title: Engineering human blood vessels for modeling and therapeutics Abstract: The differentiation, morphogenesis, and homeostasis of blood vessels occur in a complex and dynamic environment. As a result, the microenvironment plays a crucial role in vascular …
UW Biotechnology Center Auditorium @ 12:00 pm - 1:00 pm
Title: Engineering vascular endothelial cells and microphysiological system to support organ and tissue function Abstract: The vasculature plays a critical role during embryogenesis to guide tissue growth and patterning. After birth, vascular networks continue to regulate …
Orchard View Room in WID @ 12:00 pm - 1:00 pm
The University of Wisconsin-Madison Stem Cell & Regenerative Medicine Center (SCRMC) is committed to training future leaders in stem cell research. Every year, we invite senior PhD students from across the country for the Wisconsin …
UW Biotechnology Center Auditorium @ 12:00 pm - 1:00 pm
Title: Beyond Gene Dosage: Multidimensional Islet Dysfunction in Down Syndrome-Related Type 2 Diabetes Abstract: Individuals with Down syndrome are four times more likely to develop type 2 diabetes (T2D) than the general population, with onset occurring …