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Heart regeneration pioneer to join UW–Madison, Morgridge Institute

Kenneth Poss, a biologist who explores the potential life-saving mechanisms of how organisms regenerate damaged heart and spinal cord tissue will join the UW–Madison and the Morgridge Institute for Research this fall. Deneen Wellik, chair of cell and regenerative biology and a SCRMC member, says Poss is coming to Madison at a great time. “To have added such an outstanding leader will amplify our strength in this field and augment continued growth at UW–Madison. Further, expertise in imaging and genomics at UW–Madison will complement advances in regenerative biology.”

April 9, 2024

New tool provides researchers with improved understanding of stem cell aging in the brain

Researchers are one step closer to understanding the cellular mechanisms underlying stem cell aging in the brain thanks to a new tool developed at the University of Wisconsin–Madison.

March 27, 2024

SCRMC members lead the way in developing ISSCR standards that enhance reproducibility and rigor

These guidelines were developed through collaboration with researchers across the globe. Among those leading the charge were Stem Cell Regenerative Medicine Center (SCRMC) members Tenneille Ludwig, PhD, a senior scientist and director of the WiCell Stem Cell Bank, and Anita Bhattacharyya, PhD, an associate professor of Cell and Regenerative Biology at the University of Wisconsin–Madison.

March 12, 2024

UW–Madison researchers first to 3D-print functional human brain tissue

A team of University of Wisconsin–Madison scientists including SCRMC member Su-Chun Zhang have developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.

February 1, 2024

UW researchers uncover new clues about the cause of common birth defects

A recent study led by Robert Lipinski, a SCRMC member and associate professor of comparative biosciences at the UW School of Veterinary Medicine, has uncovered new information about orofacial development in mice that researchers believe could one day help reduce the risk of these birth defects in humans.

January 31, 2024

2024 SURF Program Applications Now Open

This program pairs a motivated, talented UW–Madison undergraduate student, who is in the first half of their undergraduate career and is interested in pursuing research in the regenerative medicine and stem cell sciences, with a graduate student or postdoctoral fellow mentor in one of the labs in the UW SCRMC.

January 30, 2024

Team of SCRMC members receives WARF Innovation Award  

The first 2023 WARF Innovation Award has been given to the University of Wisconsin-Madison’s Ahmed Mahmoud, assistant professor of cell and regenerative biology; Timothy Kamp, professor of medicine and director of the SCRMC; and Youngsook Lee, emeritus professor of cell and regenerative biology; for their work, Regenerating and Renewing Heart Tissue.

The team discovered a protein, LRRC10, that activates heart renewal and regeneration in animal models. This discovery could lead to a therapeutic that restores cardiac structure and function in human heart failure patients.

January 2, 2024

Stem cell technology developed at UW–Madison leads to new understanding of Autism risks

Technology developed at the University of Wisconsin–Madison to grow “rosettes” of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

December 20, 2024

UW effort to map Down syndrome brain raises prospect of treatment for disorder

SCRMC members Anita Bhattacharyya and Su-Chun Zhang discuss the brain atlas project, which involves four faculty and 15 lab researchers. It is part of a federal program started five years ago to boost research funding for Down syndrome, the most common genetic cause of intellectual disability.

October 24, 2023

Combining cell types may lead to improved cardiac cell therapy following a myocardial infarction

Researchers at the University of Wisconsin–Madison and Academia Sinica, Taiwan, have identified a novel strategy that harnesses a combination of lab-grown cells to regenerate damaged heart muscle, marking a noteworthy advancement in cardiac regeneration research.

October 17, 2023

Patient hails new UW Health dry mouth treatment a ‘game-changer’

SCRMC member and UW Health radiation oncologist, Dr. Randy Kimple discusses a new cell therapy that is currently in Phase 1 trials at UW Health. This cell therapy was developed together with the UW Program for Advanced Cell Therapy led by Dr. Jacque Gallipeau. The treatment aims to aid patients who are experiencing dry mouth as a side effect of radiation treatment.

October 13, 2023

Discovery reveals mitochondria as potential treatment target for fragile X syndrome

A new study published today in the journal Neuron by researchers at the University of Wisconsin–Madison showed that FMRP, a protein deficient in individuals with fragile X syndrome, has a role in the function of mitochondria, part of a cell that produces energy, during prenatal development. Their results fundamentally change how scientists understand the developmental origins of fragile X syndrome and suggest a potential treatment for brain cells damaged by the dysfunction.

October 10, 2024

Casey Ostheimer knows how to nurture

Explore the academic adventures of undergraduate research assistant Casey Ostheimer, who worked with SCRMC and SMPH faculty member Owen Tamplin.

September 19, 2023

Computational tool helps uncover gene networks of cell fate

New research from the Wisconsin Institute for Discovery (WID) and SCRMC member Sushmita Roy, is providing key insights that will aid researchers in constructing a more precise view of what drives cellular identity.

August 10, 2023

New research expands understanding of impact of rapamycin on fragile X syndrome

A new study led by Waisman investigator and SCRMC member Xinyu Zhao, highlights the role elevated levels of the protein MAP1B and ASD play in fragile X syndrome (FXS) symptoms and identifies a potential treatment using the FDA-approved drug rapamycin. SCRMC members and Waisman investigators Andre Sousa and Qiang Chang also contributed to the study.

July 6, 2023

SCRMC director and collaborators receive Research Forward Award

Stem Cell and Regenerative Medicine Director, Tim Kamp and a team of collaborators will receive one of sixteen Research Forward grants to study new avenues to treat heart failure using an engineered enzyme and human pluripotent stem cells.

May 31, 2023

Congratulations to the Summer Undergraduate Research Fellowship (SURF) Award Winners!

These talented undergraduate students will be paired with mentors for more than 10-weeks of collaborative research.

May 17, 2023

2023 SCRMC Research Training Award Winners Announced 

We invite you to meet the winners of the 2023 SCRMC Research Training Awards Program, which provides unique, interdisciplinary training for four future leaders in stem cell and regenerative medicine research. Additionally, this program will foster interdisciplinary collaborations among campus investigators.

April 18, 2023

Two SCRMC members receive the 2023-2024 Vilas Associates Award

Stem Cell & Regenerative Medicine members Feyza Engin and Ahmed Mahmoud have received the 2023-2024 University of Wisconsin-Madison Vilas Associates Award. This honor recognizes new and on-going research of the highest quality and significance.

April 17, 2023

SCRMC researchers identify cell type that could be key to preventing marrow transplant complication

New research from the University of Wisconsin–Madison is helping to change that by identifying the cell population that causes GVHD, a target that may make bone marrow transplants safer and more effective.

March 24, 2023

New nanocapsules deliver therapy brain-wide, edit Alzheimer’s gene in mice

Gene therapies have the potential to treat neurological disorders like Alzheimer’s and Parkinson’s diseases, but they face a common barrier — the blood-brain barrier. Now, researchers at the University of Wisconsin–Madison have developed a way to move therapies across the brain’s protective membrane to deliver brain-wide therapy with a range of biological medications and treatments.

February 1, 2023

Lab-grown retinal eye cells make successful connections, open door for clinical trials to treat blindness

A new study suggests that retinal cells grown from stem cells may be ready for trials in humans with degenerative eye disorders.

The organized clusters of cells, or organoids, used in the study were developed in the lab of David Gamm, a SCRMC member, UW–Madison ophthalmology professor, and director of the McPherson Eye Research Institute. While these organoids were developed nearly a decade ago, this is the first time that Gamm and his lab have shown that the organoids have the capacity to communicate across synapses, tiny gaps between cells. This is an important development, which indicates that these organoids can replace diseased cells and carry sensory information to the brain.

January 24, 2023

Improved understanding of early spinal cord development paves the way for new treatments

Researchers at the University of Wisconsin–Madison are developing the means to turn stem cells into a wide range of specific types of spinal cord neurons and cells in the hindbrain — the critical nexus between the spinal cord and the brain — paving the way for improved prevention and treatment of spinal cord disease.

October 18, 2022

New Department of Defense Grant to Study Fragile X Syndrome in Human Cells

A new study will characterize human stem cell models of fragile X syndrome (FXS) to better understand the mechanisms behind FXS symptoms and how those may inform the search for effective therapies. The study, which will be supported by a three-million-dollar U.S. Department of Defense (DOD) grant, will be led by Xinyu Zhao professor of neuroscience, and Anita Bhattacharyya, assistant professor of cell and regenerative biology. Both are also Waisman Center investigators and Stem Cell and Regenerative Medicine members.

October 4, 2022

SURF program prepares students to ride the waves of research

The Stem Cell and Regenerative Medicine Center labs welcomed new members this summer, as five talented undergraduate students joined mentors for more than 10-weeks of collaborative research. This unique experience is a part of the Summer Undergraduate Research Fellowship (SURF), which supports motivated University of Wisconsin–Madison undergraduate students as they pursue research in the stem cell sciences.

September 28, 2022

New study identifies protein essential to form stem cell-derived human heart cells

Lab-grown human heart cells provide a powerful tool to understand and potentially treat heart disease. However, the methods to produce human heart cells from pluripotent stem cells are not optimal. Fortunately, a new study out of the University of Wisconsin-Madison Stem Cell & Regenerative Medicine Center, is providing key insight that will aid researchers in growing cardiac cells from stem cells.

June 29, 2022

SCRMC researchers uncover how stem cell-derived photoreceptors reach their targets

A new study investigating the growth of photoreceptors may have implications for the treatment of retinal diseases that cause blindness. The study, published in Cell Reports, was led by Stem Cell and Regenerative Medicine (SCRMC) researcher Timothy Gomez, professor of neuroscience, Sarah Rempel, a postdoctoral researcher in the Gomez lab, and SCRMC researcher David Gamm, professor of ophthalmology.

June 21, 2022

Jacques Galipeau named president of the International Society for Cell and Gene Therapy

Increasing place of care manufacturing and deployment of cell therapies is a core mission for Jacques Galipeau, MD, who was recently named president of the International Society for Cell and Gene Therapy (ISCT).

June 20, 2022

Team of SCRMC researchers awarded Research Forward grant 

A team of Stem Cell & Regenerative Medicine Center (SCRMC) researchers will investigate cell therapy as a treatment for brain disorders, injuries, and aging thanks to a Research Forward grant. The project’s multidisciplinary team, which includes Principal Investigator and SCRMC member Krishanu Saha, hope that this research will lead to advancements in the treatment of neurodevelopmental and neurodegenerative disorders like Alzheimer’s and Parkinson’s Disease.

June 7, 2022

When age is more than a number: Undergraduate SCRMC lab member Samuel Neuman focuses on regenerative medicine as a way to impede diseases of degeneration and aging

Aging is part of the human experience, but not every experience is the same. Progressive neurodegenerative diseases such as Parkinson’s, Huntington’s, and Alzheimer’s disease present many challenges to patients and their families, and researchers like University of Wisconsin-Madison junior Samuel Neuman are using stem cells and regenerative medicine to find a solution. Read more

May 3, 2022

SCRMC Director Tim Kamp pens perspectives piece for Quarterly magazine

Nearly twenty-five years ago, University of Wisconsin-Madison researcher James Thomson described the first successful derivation of human embryonic stem cells (hESCs). These cells, which are pluripotent, meaning they can form any cell type and self-renewing, meaning they can grow indefinitely in culture, changed the way diseases are understood and treated. While the past two decades have included dramatic advances, there is still much to learn, and clinical trials are just beginning for a variety of degenerative diseases. Dr. Kamp outlines the opportunities, challenges, and the history of stem cell research in his column “Stem Cells and Regenerative Medicine: A long, but promising road” available on page 40 of the spring 2022 Quarterly magazine.  

May 2, 2022

SMPH

Hundreds attend 16th Wisconsin Stem Cell Symposium focusing on stem cell competition

On April 20, 2022, more than 260 students and researchers gathered for the 16th Wisconsin Stem Cell Symposium in Madison, Wis. Co-hosted by the Stem Cell and Regenerative Medicine Center (SCRMC) and the BioPharmaceutical Technology Center Institute (BTC Institute), this annual event highlights the latest advances in stem cell science and technology. This year, the symposium focused on stem cell competition, which has important implications for healthy aging and disease states.

Throughout the day, virtual and in-person attendees heard from seven of the world’s leading researchers studying stem cell competition. Additionally, attendees participated in a rapid-fire poster session that included twelve presentations by graduate and post-doctoral researchers. The conversation continued during the lunch and networking session, with the rapid-fire presenters as well as eighteen other researchers sharing their posters throughout the event hall.

The SCRMC and the BTC Institute thank all who attended as well as the sponsors who helped to make this event a success.

Team of SCRMC researchers help to improve quality control for biomanufacturing stem cells

A team of University of Wisconsin-Madison researchers, including members of the Stem Cell and Regenerative Medicine Center (SCRMC), have developed an innovative methodology that can ultimately be used to advance cutting-edge personalized therapies and disease models.

The study, published in the journal GEN Biotechnology, outlines the new methodology which includes a real-time method for tracking the reprogramming of somatic cells to induce pluripotent stem cells (iPSCs) using micropatterning, label-free imaging, and machine learning.

This novel study was led by Kaivalya Molugu, a recent PhD graduate in biophysics who worked in SCRMC faculty member and College of Engineering Associate Professor, Krishanu Saha’s lab where Molugu was funded through a Stem Cell and Regenerative Graduate fellowship. The study was a collaborative project with SCRMC faculty member and Professor of Biological Engineering, Melissa Skala’s lab.

April 21, 2022

College of Engineering

SCRMC lab member Samuel Neuman receives 2022 Barry Goldwater Scholarship

University of Wisconsin-Madison biochemistry and biomedical engineering student Samuel Neuman has been awarded the 2022 Barry Goldwater Scholarship. This prestigious scholarship recognizes outstanding undergraduate students who are pursuing careers in science and was awarded, in part, due to Neuman’s work in Stem Cell and Regenerative Medicine Center (SCRMC) faculty member Marina Emborg’s Preclinical Parkinson’s Research Program.

As a member of Emborg’s lab, Neuman studies vehicles for delivering CRISPR/Cas9 gene-editing reagents to the brain of multiple model organisms. Through this work, Neuman has earned authorship on a soon-to-be published manuscript. Neuman is also beginning research into a strategic neural-network therapy for Parkinson’s disease and will be conducting research at the National Institute of Child Health and Human Development later this year.

April 18, 2022

A science trailblazer retires: Stem cell researcher James Thomson’s legacy changed the future of biology

James Thomson helped the scientific world turn its attention to the shape-shifting stem cells that give rise to all of the building blocks of complex living organisms, from skin and bone, to hearts and blood, to neurons and brains.

After more than 30 years with the University of Wisconsin–Madison and 15 years with the Morgridge Institute for Research, Thomson has announced plans to retire in July 2022.

“There are few scientists in the world, across all of history, with the ability to translate their deep curiosity about life into discoveries that fundamentally change what’s possible for humanity,” says UW–Madison Chancellor Rebecca Blank. “We are all fortunate that Jamie Thomson dedicated his own life and career to such pursuits, and we are especially grateful he did so at UW–Madison. His work has influenced generations of our students and scholars.”

March 3, 2022
Morgridge Institute for Research

UW study finds photoreceptor cells from retinal organoids can replicate key functions of vision

Researchers from the University of Wisconsin School of Medicine and Public Health have successfully shown that a retinal cell type derived from human pluripotent stem cells is capable of the complex process of detecting light and converting that signal to electrical waves. Co-author and Stem Cell Center member, Dr. Gamm noted, “The more we can push retina organoids to perform at a high level in a [cell culture] dish, the more confidence we have that they may help patients with blinding disorders. So, it’s a big leap in human pluripotent stem cell technology in terms of its applications to retinal disease.”

February 2, 2022
SMPH News

Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment

Gain-of-function mutations in the GFAP gene are the cause of Alexander disease (AxD), a leukodystrophy characterized by motor and cognitive impairments and seizures, among other symptoms. Co-researchers from the Messing Lab at UW-Madison’s Waisman Center helped develop a rat model of AxD that closely mimics the clinical phenotype and showed that the animals developed the major hallmarks of AxD as they matured.

Nov. 18, 2021
Science Translational Medicine

UW Health treats first patient in U.S. with investigational cell therapy for heart disease

Appleton resident Donald Krause became the first patient in the country last week to undergo an investigational cell therapy for a debilitating heart condition called chronic myocardial ischemia (CMI). Krause was treated by Amish Raval, MD, an interventional cardiologist at UW Health, supported by Peiman Hematti, MD, a bone marrow transplantation hematologist at the UW School of Medicine and Public Health.

October 29, 2021
SMPH News

Stem cell project to create new model to study brain development and Down syndrome

Center members Dr. Anita Bhattacharyy and Dr. Su-Chun Zhang, in collaboration with Waisman and the University of Washington-Seattle and Seattle Children’s Hospital, have been awarded an $11 million Transformative Research grant from the National Institutes of Health to create a new approach using stem cells that may reveal how brain development in individuals with Down syndrome differs from typically developing individuals, identify features that will help understand their intellectual disability, and find potential targets for therapy. They will also address questions that remain unanswered about brain development overall.

October 7th, 2021
UW News

FDA approves Madison-based skin graft technology to treat burns

The U.S. Food and Drug Administration on Tuesday approved StrataGraft, a topical treatment for severe burns made from skin tissue, providing a boost for Madison-based firm Stratatech. Stratatech was founded in 2000 by SCRMC member Lynn Allen-Hoffman, the first female University of Wisconsin-Madison faculty member to start a biotech company.

June 16, 2021
The Cap Times

UW Begins New Clinical Trial to Treat Fatal Blood Disease in Children, Young Adults

The Food and Drug Administration-approved trial will use a form of transplant that replaces a patient’s bone marrow with alpha-beta T-cell depleted peripheral blood stem cells from closely matched unrelated donors or family members.

May 27, 2021

Stem Cell Research: Celebrating 25 Years Of Amazing Discoveries

Over the past two decades, stem cell research at UW-Madison has grown from involving a handful of scientists to nearly 100 from more than 30 schools, colleges and departments.

May 25, 2021
Quarterly Magazine, Vol. 23, No. 1

SCRMC member Daniel Z. Radecki recognized for his commitment to improving the lives of all postdocs

Nine University of Wisconsin–Madison postdoctoral researchers have been recognized with the inaugural Postdoc Excellence Awards for their teaching, service and mentoring. Daniel Z. Radecki (Comparative Biosciences) received one of these awards.

“The defining feature of Dan’s work with the (UW–Madison Postdoctoral Association) and others is his commitment to bettering the lives of all postdocs. He envisions how each event and initiative can best impact the individual, through the lenses of diversity and inclusion, immigration status, postdocs’ personal lives (e.g. childcare considerations), department/discipline, and more.”

Congratulations, Daniel!

April 29, 2021

Micro-molded ‘ice cube tray’ scaffold is next step in returning sight to injured retinas

Researchers at UW–Madison have made new photoreceptors from human pluripotent stem cells. However, it remains challenging to precisely deliver those photoreceptors within the diseased or damaged eye so that they can form appropriate connections, says David Gamm, director of the McPherson Eye Research Institute and professor of ophthalmology and visual sciences at the UW School of Medicine and Public Health.

“While it was a breakthrough to be able to make the spare parts — these photoreceptors — it’s still necessary to get them to the right spot so they can effectively reconstruct the retina,” he says. “So, we started thinking, ‘How can we deliver these cells in a more intelligent way?’ That’s when we reached out to our world-class engineers at UW–Madison.”

Metabolic switch may regenerate heart muscle following heart attack

Research from the University of Wisconsin–Madison finds that a new therapeutic approach for heart failure could help restore cardiac function by regenerating heart muscle. In a study recently published in the journal Circulation, the UW team describes its success in improving, in a mouse model, the function of heart muscle by temporarily blocking a key metabolic enzyme after a heart attack. This simple intervention, the researchers say, could ultimately help people regain cardiac function. “Our goal was to gain new understanding of how the heart can heal itself following injury at the molecular and cellular level and see if there was a way to restore cardiac function to an earlier state,” says UW–Madison’s Ahmed Mahmoud, professor of cell and regenerative biology in the School of Medicine and Public Health.

Learn more about the research here.
April 15, 2021

Clinical Hematopoietic Cell Processing Laboratory achieves more than minimal manipulation accreditation from FACT

Peiman Hematti, MD, is the director of Clinical Hematopoietic Cell Processing Laboratory at UW-Madison. Much of his research is aimed at improving post-transplant immunological complications, such as graft-versus-host disease. But Hematti and his team are also working to develop and test new cellular therapies for cancer treatment.

His lab’s ability to do that took a giant step forward in late 2020 when they received word from FACT – the Foundation for the Accreditation of Cellular Therapy – that the lab had received certification to do “more than minimal cell manipulation.”

“This is a big deal,” Hematti said. “We are the only lab on campus that has this accreditation, which is the culmination of years of working hard and proving that we can do it right and credit goes to our entire team and especially our senior cell therapy lab specialists.”

April 7, 2021

UW Health

Individualized brain cell grafts reverse Parkinson’s symptoms in monkeys

Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison reported today. In a study published in the journal Nature Medicine the UW team describes its success with neurons made from cells from the monkeys’ own bodies after reprogramming to induced pluripotent stem cells. UW–Madison neuroscientist Su-Chun Zhang, whose Waisman Center lab grew the brain cells, said this approach avoided complications with the primates’ immune systems and takes an important step toward a treatment for millions of human Parkinson’s patients. Learn more about their work here.
March 1, 2021

UW vision researchers partner with U.S. Department of Defense to develop stem cell therapy for combat-related eye injuries

The project, led by David Gamm, MD, PhD, director of the McPherson Eye Research Institute and professor of ophthalmology and visual sciences at the UW School of Medicine and Public Health, will develop a transplantable patch to restore vision to members of the armed forces who have been injured by blasts or lasers.
December 11, 2020

New Visualization Method Gets to the Heart of Parkinson’s Disease

This week, the NIH Office of Research Infrastructure Programs highlights Dr. Marina Emborg, her WNPRC lab team and their UW–Madison colleagues’ advances in detecting heart disease in Parkinson’s and evaluating new therapies that specifically target nerve disease within the human heart.
December 2020

Celebrating 25 Years of Embryonic Stem Cell Research at UW–Madison

It’s been 25 years since University of Wisconsin–Madison scientist James Thomson became the first in the world to successfully isolate and culture primate embryonic stem cells. He accomplished this breakthrough first with nonhuman primates at the Wisconsin National Primate Research Center in 1995, using rhesus monkey cells, then in 1996 with marmoset cells. Thomson then published his world-changing breakthrough on human embryonic stem cell derivation in Science on Nov. 6, 1998.
November 6, 2020

Study points way to possible new treatment for ligament injuries

“EEMs and exosomes each have attractive characteristics as therapeutics,” Dr. Hematti, UW-Madison’s Department of Medicine, noted.” As a cell therapy, EEMs will not proliferate or differentiate to undesirable cell types, which remains a concern for many stem cell therapies. Moreover, EEMs could be generated from a patient’s own monocytes using off-the-shelf exosomes, resulting in a faster and more facile process compared to autologous MSCs. Alternatively, exosome therapy could be a cell free, shelf-stable therapeutic to deliver biologically active components.” “Altogether, we believe our studies’ results support the use of EEMs and/or exosomes to improve ligament healing by modulating inflammation and tissue remodeling,” Dr. Vanderby concluded.
November 3, 2020

Peiman Hematti helps steer future of cell therapy

Advance furthers stem cells for use in drug discovery, cell therapy

Since highly versatile human stem cells were discovered at the University of Wisconsin–Madison nearly 20 years ago, their path to the market and clinic has been slowed by a range of complications.

Both embryonic stem cells and induced pluripotent stem cells are valued for their ability to form any cell in the body.

Department of Medicine Faculty Members Awarded UW2020 Funding

7th June 2017
A project entitled “‘Cardioimmunotherapy’ – A Paradigm Shifting Concept: Engineering Cardio-Reparative Macrophages by Cardiac Specific Exosomes” led by Co-Principal…

30th May 2017
Scientists are poised to get a better look at the fundamental development of the cells that make up blood vessels and how they can be more reliably cultured in the laboratory dish. Writing this week…

16th May 2017
The blood-brain barrier is biology’s proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in…

14th April 2017
“Patients living with heart failure experience a variety of negative symptoms that can greatly impact their day-to-day life,” said UW Health cardiologist and SCRMC member  Dr. Amish…

14th April 2017
Scientists get funded for their ideas through a marathon grant-writing process, scores of collaborators, weeks of information gathering and a final product that often tops 250 pages. SCRMC Member…

12th April 2017
A cell-therapy approach first discovered at the UW Carbone Cancer Center (UWCCC) in 2009 may reduce complications from bone marrow transplant (BMT) and radiation injury in the future, according to a…

29th March 2017
A research assistant uses a pipette to change media that feed trays of human embryonic stem cell cultures in a UW-Madison research lab. Many of UW stem cell pioneer James Thomson’s landmark…

20th March 2017
Human fibroblast cells, common connective tissue cells, growing on decellularized parsley. A team of UW-Madison researchers from the lab of bioengineering Professor William Murphy is exploring the…

27th February 2017
The mystery of what controls the range of developmental clocks in mammals — from 22 months for an elephant to 12 days for an opossum — may lie in the strict time-keeping of pluripotent stem cells…

14th February 2017
Two University of Wisconsin–Madison experts served on the 22-member international committee that compiled the report: SCRMC member R. Alta Charo, a professor of law and bioethics who co-chaired…

8th February 2017
Wednesday Nite at the Lab, Wednesday, February 08, 2017, with SCRMC member David Gamm. Video: Making Sense of Stem Cells: Progress toward the Treatment of Blinding Disorders

2nd February 2017
The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key…

20th January 2017
Bill Murphy, a professor of biomedical engineering, founded Stem Pharm, a company that plans to market systems drug-makers can use to evaluate the safety and utility of medications. Stem Pharm Inc.,…

19th January 2017
A recent study from Waisman Center researcher and SCRMC member Xinyu Zhao’s lab shows how a gene called MBD1 plays an important role in maintaining the identity of neural stem cells and…

17th January 2017
JangoBio’s solution, based on research spearheaded by the company’s CEO and UW-Madison medical professor Craig Atwood, would introduce manufactured reproductive gland cells into a patient as…

2nd January 2017
SCRMC Members Peiman Hematti (Medicine), Christian Capitini (Pediatrics), and Jacques Galipeau (Medicine) and many others synergistically have combined forces around the newest frontier in the war on…

5th December 2016
Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods. The…

29th November 2016
A longtime UW School of Medicine and Public Health professor was recently awarded the 2016 MacLean Center Prize in Clinical Ethics and Health Outcomes. SCRMC member Norman Fost, professor emeritus…

16th November 2016
SCRMC member, Dr. Darcie Moore, assistant professor in the Department of Neuroscience at the University of Wisconsin School of Medicine and Public Health, was recently honored nationally for her…

15th November 2016
The prospect of creating artery “banks” available for cardiovascular surgery, bypassing the need to harvest vessels from the patient, could transform treatment of many common heart and vascular..

1st November 2016
Ben Dungar examines neural cells in the BrainXell lab. David Tenenbaum Leaders of the University of Wisconsin-Madison lab that first transformed human stem cells into brain cells have started a…

25th October 2016
University of Wisconsin–Madison engineers are manufacturing highly personalized cancer treatments that take advantage of a patient’s own cells to attack tumors. These so-called chimeric…

13th October 2016
In 2014, when University of Wisconsin–Madison engineers announced in the journal Nature Communications that they had developed transparent sensors for use in imaging the brain, researchers around the…

7th October 2016
A research team at University of Wisconsin School of Medicine and Public Health has identified how a particular collection of proteins plays a critical role in the development of red blood cells,…

29th September 2016
Wisconsin industry leaders need to collaborate more if the state wants to become a national hub for biomanufacturing, a panel of experts agreed. The panel, speaking at the annual BioHealth Summit in…

21st September 2016
The promise of stem cells to treat cardiovascular disease may soon be a step closer to clinical application as scientists from three institutions seek to perfect and test three-dimensional “heart…

6th September 2016
The first recipient of the Jenni and Kyle Professorship is SCRMC member Xinyu Zhao, a professor in the Department of Neuroscience and a Waisman investigator. Zhao’s research focuses on…

1st September 2016
A UW-Madison research team has been selected to work on one of six projects aimed at restoring vision by regenerating light-sensing photoreceptor cells in the eye. SCRMC member Dr. David Gamm,…

18th August 2016
In another step toward unraveling the causes of serious blood disorders, a UW-Madison research team has identified how a genetic network in certain blood cells can be disrupted and go on to promote…

4th August 2016
We are pleased to announce that 14 highly-innovative research projects have been chosen for the second round of funding for the UW2020: WARF Discovery Initiative. The projects include research and…

5th July 2016
It may seem odd at first that there are researchers at the UW Carbone Cancer Center who study viruses, those tiny particles that do not develop cancer themselves because they are not even alive. But…

17th May 2016
Phil Newmark, a developmental biologist studying the mysteries of how the body regenerates damaged tissue, will join the Morgridge Institute for Research and the University of Wisconsin-Madison…

13th May 2016
Two graduating seniors and a current medical student at the University of Wisconsin—Madison have won National Institutes of Health Oxford-Cambridge Scholarships, a rare honor for students…

5th May 2016
Twelve promising young members of the UW–Madison faculty have been honored with Romnes Faculty Fellowships. Romnes awards recognize exceptional faculty members who have earned tenure within…

2nd May 2016
At the 23rd Annual Conference of the American Society of Neural Therapy and Repair (ASNTR), held April 28-30, 2016 in Clearwater Beach, Florida, ASNTR awarded The 2016 Bernard Sanberg Memorial Award…

28th April 2016
Standing at center, Su-Chun Zhang talks with his staff as they prepare stem cell cultures at UW-Madison’s Waisman Center. Photo: Jeff Miller A University of Wisconsin-Madison neuroscientist has…

8th April 2016
“Stem Cells in the 4th Dimension,” an annual scientific meeting coordinated by the Stem Cell and Regenerative Medicine Center at the University of Wisconsin-Madison and the..

17th March 2016
In one of the first studies to “read” the genetic activity inside individual brain cells, University of Wisconsin-Madison neuroscientist Xinyu Zhao has identified the genetic machinery…

26th February 2016
Elizabeth Donley Photo: Greg Theune A University of Wisconsin-Madison spinoff is screening blood samples in an effort to develop a biologically based method to diagnose autism. The company, Stemina…

11th February 2016
Induced cardiac progenitor cells (iCPCs) can develop in a dish into contracting heart muscle cells (green) when grown together with other contracting heart muscle cells. These cells could…

25th January 2016
When the body has a low blood cell count, it can have trouble fighting off infection. But transfusible blood products may be in the not-so-distant future.

12th January 2016
An uncommon and little-studied type of cell in the lungs has been found to act like a sensor, linking the pulmonary and central nervous systems to regulate immune response in reaction to…

15th December 2015
Nearly 1,000 scientists and staff at the University of Wisconsin–Madison joined a growing chorus of objections to a state proposal to ban the use of fetal tissue in life-saving biomedical research by…

14th December 2015
Su-Chun Zhang, a pioneer in developing neurons from stem cells at the University of Wisconsin-Madison, has created a specialized nerve cell that makes serotonin, a signaling chemical with a broad…

1st December 2015
By generating cells with the properties of primitive human leukemia cells, researchers have established a model for studying chronic myeloid leukemia (CML) stem cells, potentially leading to better…

5th October 2015
As she watched the surgeon operating on a farmer who had suffered third-degree burns across 95% of his body, researcher Lynn Allen-Hoffmann realized instantly she had a new mission: making human skin…

24th September 2015
Proposed legislation in Wisconsin will have a devastating impact on the ability of researchers to create lifesaving treatments for patients, Robert Golden, dean of the University of Wisconsin-Madison…

22nd September 2015
The Board of Trustees of the Wisconsin Alumni Research Foundation (WARF) today announced unanimous opposition to a state legislative proposal to ban the use of fetal tissue in scientific research.

21st September 2015
A new system developed by scientists at the Morgridge Institute for Research and the University of Wisconsin-Madison may provide a faster, cheaper and more biologically relevant way to screen drugs…

8th September 2015
Madison, Wisconsin – Researchers at the University of Wisconsin-Madison have revealed the function of a small chromosome segment directly responsible for a subset of myeloid leukemias. Knowing the…

4th August 2015
President Barack Obama has named University of Wisconsin-Madison biochemistry Professor Judith Kimble to chair the President’s Committee on the National Medal of Science. Established by Congress…

3rd August 2015
In a multidisciplinary effort, a team of University of Wisconsin-Madison engineers has identified a protein that is integral to the survival and self-renewal processes of human pluripotent stem cells…

30th July 2015
Ian Duncan, a professor of neurology at the University of Wisconsin-Madison School of Veterinary Medicine and a world leader in the study of myelin disorders of the central nervous system, has…

21st July 2015
Su-Chun Zhang, SCRMC member, who joined the UW–Madison neuroscience and neurology faculty in 2001, is the new Steenbock Professor of Behavioral & Neural Sciences.

21st July 2015
In his 19-year career at UW–Madison, Dr. Su-Chun Zhang has transformed the field of stem cell research. The renowned neuroscientist was the first in the world to isolate neural stem cells from…

18th July 2015
Stem cell research at UW-Madison typically aims to create skin and organs; this summer, its goal is to create scientists. Twenty small-town Wisconsin high school students and teachers, alongside UW-…

2nd July 2015
Applying a dramatically improved method for “editing” genes to human stem cells, University of Wisconsin-Madison neuroscientist Su-Chun Zhang has shown a new way to silence genes in stem cells and…

19th June 2015
The news that legendary Green Bay Packer quarterback Bart Starr has undergone stem cell therapy to recover from a stroke has raised the profile for a promising but unproven regenerative treatment…

17th June 2015
Madison, Wisconsin – Using big data and state-of-the-art gene editing techniques, a team of University of Wisconsin-Madison researchers have identified dozens of genes they believe regulate blood…

16th April 2015
Limb regeneration, stem cells, limb development, tissue engineering: These will be the focus of the 10th Annual Wisconsin Stem Cell Symposium on Wednesday, April 22, hosted by the University of…

25th March 2015
Even in an era in which there is increased emphasis on living “green,” humans are constantly exposed to a wide range of toxins in everything from our air, food and water to the goods we buy…

8th January 2015
University of Wisconsin researchers are laying the groundwork to make it possible to “print” new transplant-ready organs, grown from cells cultured from a patient’s blood sample. This project, which…

21st December 2014
Drugs that seem safe in animal studies are sometimes found to be harmful in humans. The health effects of many chemicals on the market — in products such as cosmetics, food additives and…

24th November 2014
Four members of the University of Wisconsin–Madison faculty have been elected fellows of the American Association for the Advancement of Science (AAAS), the society announced today. Two of the…

13th November 2014
One remarkable quality of pluripotent stem cells is they are immortal in the lab, able to divide and grow indefinitely under the right conditions. It turns out this ability also may exist further…

23rd September 2014
A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals…

8th September 2014
In a new study, a team of researchers from the University of Wisconsin-Madison has added a new wrinkle to the cell differentiation equation, showing that the stiffness of the surfaces on which stem…

26th August 2014
As UW-Madison’s research and graduate education programs begin an historic transition, there will be many familiar faces and a few new ones on the third floor of Bascom Hall. This month, a new…

14th July 2014
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Writing today (July 14, 2014) in the journal Nature…

11th June 2014
Madison, Wisconsin – Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even…

24th April 2014
World stem cell leaders will converge on Promega’s BioPharmaceutical Technology Center in Fitchburg on April 30 for the 9th Annual Wisconsin Stem Cell Symposium: From Stem Cells to Blood.

3rd April 2014
By studying nerve cells that originated in patients with a severe neurological disease, a University of Wisconsin-Madison researcher has pinpointed an error in protein formation that could be the…

24th March 2014
Desperate patients are easy prey for unscrupulous clinics offering untested and risky stem cell treatments, says law and bioethics Professor Alta Charo of the University of Wisconsin-Madison, who is…

21st March 2014
As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal…

3rd March 2014
A team of University of Wisconsin-Madison researchers has induced human embryonic stem cells (hESC) to differentiate toward pure-population, mature heart muscle cells, or cardiomyocytes.

10th January 2014
A team of engineers at the University of Wisconsin-Madison has created a process to improve the creation of synthetic neural stem cells for use in central nervous system research.

5th January 2014
After Susan Derse Phillips had chemotherapy for leukemia, she received a stem cell transplant, getting blood-forming cells from a donor to restore her immune system and attack any remaining leukemia…

2nd December 2013
University of Wisconsin School of Medicine and Public Health (SMPH) researchers have discovered a very early regulatory event that controls the production of blood stem cells and the adult blood…

7th November 2013
With last Friday’s retirement of longtime University Research Park Director Mark Bugher, associate director Greg Hyer is assuming the role of interim director of the successful, 260-acre park on the…

29th October 2013
The investment made in science at UW–Madison and colleges and universities across the United States helps drive the country’s economy directly through the creation of new companies based…

17th October 2013
Developing a new drug takes enormous amounts of time, money and skill, but the bar is even higher for a promising stem-cell therapy. Many types of cells derived from these ultra-flexible parent cells…

26th September 2013
What if you could travel back in time 3 billion years, and take a breath? What would earth’s air smell like? Deeply stinky, according to Brooke Norsted, an outreach specialist for the University of…

5th September 2013
Rebecca Blank arriving, Kevin Reilly leaving. Budget cuts and tuition freezes. Even if you were vacationing and unplugged over the summer, it was hard to miss these headlines. But you can be excused…

12th August 2013
Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to…

9th July 2013
You simply can’t remember where you put your keys. It’s fine, happens to everybody and you are just getting older. Good-humoredly, you even start calling yourself “absentminded….

26th June 2013
Many scientists use animals to model human diseases. Mice can be obese or display symptoms of Parkinson’s disease. Rats get Alzheimer’s and diabetes. But animal models are seldom perfect, and so…

13th June 2013
With a simple skin biopsy, scientists can reverse-engineer a few of your skin cells and create genetically identical stem cells called induced pluripotent stem (iPS) cells. Take it a few steps…

28th May 2013
MADISON, Wis. — Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease…

27th May 2013
In new research published this week, Anita Bhattacharyya, a neuroscientist at the Waisman Center at the University of Wisconsin-Madison, reports on brain cells that were grown from skin cells of…

24th May 2013
The Greater Milwaukee Foundation has chosen two University of Wisconsin-Madison researchers for 2013 Shaw Scientist Awards.

2nd May 2013
A University of Wisconsin-Madison research group has converted skin cells from people and monkeys into a cell that can form a wide variety of nervous-system cells – without passing through the do-it-…

2nd May 2013
The drug trial is not off to an auspicious start. The cells are not cooperating.

21st April 2013
For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember.

10th April 2013
When it comes to delivering genes to living human tissue, the odds of success come down the molecule. The entire therapy – including the tools used to bring new genetic material into a cell – must…

8th April 2013
World leaders in the use of stem cells will gather Wednesday, April 10 at the BioPharmaceutical Technology Center Institute in Fitchburg, Wis., for the eighth annual Wisconsin Stem Cell Symposium, “…

4th April 2013
A prestigious scientific honor adds to the legacy of stem cell pioneer James Thomson.

14th March 2013
For the first time, scientists have transplanted neural cells derived from a monkey’s skin into its brain and watched the cells develop into several types of mature brain cells, according to the..

21st February 2013
Eight outstanding faculty members at the University of Wisconsin-Madison have been named winners of this year’s Kellett Mid-Career Awards. Included in the eight was Emery Bresnick,..

12th February 2013
The ultimate cause of hearing loss is usually found in the tiny hair cells that play the crucial role of converting sound waves into nerve impulses for delivery to the brain.

24th January 2013
From her perch as director of the Waisman Center, and with an insider’s knowledge of its work to advance our understanding of developmental disability and the people it affects, Marsha Mailick sees a…

8th January 2013
A new study, published online in the American Journal of Respiratory and Critical Care Medicine and conducted largely at the University of Wisconsin-Madison, shows the potential for two complimentary…

7th January 2013
The US Supreme Court today ended an effort to shut down government support of human embryonic stem cell research, refusing to hear a case that challenged the legality of funding for the work by the…

18th November 2012
The science behind the medical research involving the Reese family of McHenry might be difficult to explain. Tim Reese and his sister, Theresa Selzer of Woodstock, recently donated skin cells in a…

13th November 2012
The Institute for Biology Education and Steenbock Library have launched a joint Educational Innovation project to create a biology community and learning center for bioscience students across campus…

16th October 2012
Mario Capecchi, winner of the 2007 Nobel Prize in Physiology and Medicine, will deliver the 2012 Rennebohm Lectures at UW-Madison on Monday and Tuesday, Oct. 22 and 23.

26th September 2012
Stem cells are biological building blocks, the starting point of human life. But without proper direction, they’re not very useful when it comes to treating disease.

10th September 2012
The protein GATA2 is known as a “master regulator” of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can…

8th August 2012
An interdisciplinary team of scientists and engineers at the University of Wisconsin-Madison has received a $1 million grant from the W.M. Keck Foundation to fund research into creating synthetic…

24th July 2012
With a $2.2 million grant from the National Institutes of Health, stem cell pioneer Dr. James Thomson, University of Wisconsin–Madison associate professor of biomedical engineering William Murphy and…

17th July 2012
Eighteen top science students from northern Wisconsin high schools have earned the opportunity to hone their laboratory skills and work alongside leading researchers from the University of Wisconsin-…

29th June 2012
Dr. David Gamm, whose lab is internationally known for deriving human retina cells and tissue-like structures from human stem cells, has been selected as director of the University of Wisconsin Eye…

25th June 2012
The blood-brain barrier — the filter that governs what can and cannot come into contact with the mammalian brain — is a marvel of nature. It effectively separates circulating blood from the fluid…

30th May 2012
Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in…

28th May 2012
Cardiomyocytes, the workhorse cells that make up the beating heart, can now be made cheaply and abundantly in the laboratory.

19th April 2012
Bill Murphy is an associate professor of biomedical engineering,materials science and engineering, and orthopedics and rehabilitation. Murphy and his students develop new biomaterials and uses for…

4th April 2012
Scientific leaders in the use of stem cells to solve scientific and medical problems will gather Wednesday, April 11 at the BioPharmaceutical Technology Center Institute in Fitchburg, just south of…

15th March 2012
Huntington’s disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a…

13th March 2012
For the first time, scientists at the University of Wisconsin-Madison have made early retina structures containing proliferating neuroretinal progenitor cells using induced pluripotent stem (iPS)…

8th March 2012

UW Law Professor R. Alta Charo was senior policy adviser to the commissioner at the Food and Drug Administration from August 2009 until June 2011. Now back on campus, Charo spoke reflects on her time…


5th March 2012
The Wisconsin Institutes for Discovery, the innovative 330,000-sqaure-foot public-private facility that opened just more than a year ago on the UW–Madison campus, has been named the 2012 Laboratory…

3rd February 2012
Using lab-grown human neurons, researchers from the University of Wisconsin-Madison have devised an effective assay for detecting botulinum neurotoxin, the agent widely used to cosmetically smooth…

21st November 2011
Among the many hurdles to be cleared before human embryonic stem cells can achieve their therapeutic potential is determining whether or not transplanted cells can functionally integrate into target…

11th September 2011
Ever since human induced pluripotent stem cells were first derived in 2007, scientists have wondered whether they were functionally equivalent to embryonic stem cells, which are sourced in early…

26th July 2011
Eighteen students participating in the inaugural Global Wisconsin Idea Program — a unique pairing of American and Chinese teenagers — will join a Chinese university dean this week to learn more…

15th June 2011
Soon, some treatments for blinding eye diseases might be developed and tested using retina-like tissues produced from the patient’s own skin, thanks to a series of discoveries reported by a team of…

22nd May 2011
Pity the lowly astrocyte, the most common cell in the human nervous system.

21st April 2011
The sixth annual Wisconsin Stem Cell Symposium, Reprogramming and Controlling Stem Cell Phenotype, will be held April 27 at Madison’s BioPharmaceutical Technology Center Institute.

4th April 2011
Scientists from the Morgridge Institute for Research, the University of Wisconsin-Madison, the University of California and the WiCell Research Institute moved gene therapy one step closer to…

16th March 2011
In recognition of his pioneering work in isolating human stem cells and the promise they hold for the future of medicine, Wisconsin researcher James Thomson has been named a co-recipient of the 11th…

4th February 2011
By coaxing healthy and diseased human bone marrow to become embryonic-like stem cells, a team of Wisconsin scientists has laid the groundwork for observing the onset of the blood cancer leukemia in…

21st January 2011
James Thomson, director of regenerative biology at the Morgridge Institute for Research and a University of Wisconsin-Madison researcher since 1994, learned this week that he is this year’s co-winner…

14th November 2010
Growing human embryonic stem cells in the lab is no small feat. Culturing the finicky, shape-shifting cells is labor intensive and, in some ways, more art than exact science.

9th September 2010
A panel of appellate judges removed barriers to embryonic stem cell research funded by federal grants in a decision Thursday, Sept. 9 reversing a suspension of funding ordered in August by another…

1st July 2010
With more than 100 billion neurons and billions of other specialized cells, the human brain is a marvel of nature. It is the organ that makes people unique.

27th April 2010
Today the National Institutes of Health reapproved the WiCell Research Institute’s H9 (WA09) human embryonic stem (ES) cell line, the most used and cited in scientific research, for ongoing use in…

15th April 2010
The fifth annual Wisconsin Stem Cell Symposium, called “The Road to Stem Cell Applications: Bioprocessing, Safety and Preclinical Evaluation,” will be held on Wednesday, April 21 just outside of…

9th March 2010
A year after President Barack Obama issued a landmark executive order to remove eight years of limitations on U.S. federal funding of stem cell research, the WiCell Research Institute has expanded…

15th February 2010
The great promise of induced pluripotent stem cells is that the all-purpose cells seem capable of performing all the same tricks as embryonic stem cells, but without the controversy.

10th February 2010
The Morgridge Institute for Research has finalized its inaugural team of top scientists selected to bring to life the institute’s mission of accelerating discovery to delivery to improve human health.

3rd February 2010
When it comes to stem cell research as a political issue, Wisconsin voters are more likely to be motivated by ideas of economic benefit and scientific progress than by religious objections, according…

29th January 2010
The WiCell Research Institute can continue to provide stem cell scientists one of the earliest and most popular human embryonic stem cell (hESC) lines in the field for their use in federally funded…

26th January 2010
The long struggle to move the most versatile stem cells from the laboratory to the clinic got another boost with an $8.8 million contract award to the Waisman Clinical Biomanufacturing Facility at…

11th January 2010
While much of the promise of stem cells springs from their ability to develop into any cell type in the body, the biological workings that control that maturation process are still largely unknown.

15th September 2009
Four advanced pieces of scientific laboratory equipment with a total value of approximately $1 million now are available for use by University of Wisconsin-Madison stem cell and other researchers at…

24th August 2009
A team of scientists from the University of Wisconsin-Madison School of Medicine and Public Health has successfully grown multiple types of retina cells from two types of stem cells – suggesting a…

11th August 2009
In an advance that could help transform embryonic stem cells into a multipurpose medical tool, scientists at the University of Wisconsin-Madison have transformed these versatile cells into…

6th July 2009
The WiCell Research Institute and the Waisman Clinical Biomanufacturing Facility (WCBF) announced today (July 6) the release of the first current Good Manufacturing Practices (cGMP) feeder-…

6th May 2009
Pfizer Inc., a major biopharmaceutical company, and the Wisconsin Alumni Research Foundation (WARF), the private, nonprofit patenting and licensing organization for the University of Wisconsin-..

26th March 2009
A team of scientists from the Morgridge Institute for Research at the University of Wisconsin-Madison reports that it has created induced human pluripotent stem (iPS) cells completely free of viral…

9th March 2009
Following is a statement from James Thomson, University of Wisconsin-Madison professor of anatomy, on President Barack Obama’s decision to lift restrictions on federal funding for human embryonic..

12th February 2009
A little more than a year after University of Wisconsin-Madison scientists showed they could turn skin cells back into stem cells, they have pulsating proof that these “induced” stem cells can indeed…

15th January 2009
Cellartis AB, a premier provider of human embryonic stem cell (hES) derived products and technologies, and the Wisconsin Alumni Research Foundation (WARF), the private, nonprofit patenting and…

12th January 2009
The U.S. National Stem Cell Bank (NSCB) has announced that it has received deposits of two human embryonic stem cell lines from Cellartis AB, a biotechnology company based in Sweden. With the…

22nd December 2008
When neurons started dying in Clive Svendsen’s lab dishes, he couldn’t have been more pleased. The dying cells – the same type lost in patients with the devastating neurological disease spinal…

18th December 2008
James Thomson, director of regenerative biology at the Morgridge Institute for Research and John D. MacArthur Professor at the University of Wisconsin-Madison School of Medicine and Public Health,…

18th December 2008
VistaGen Therapeutics and the Wisconsin Alumni Research Foundation (WARF) have signed a license for human embryonic stem cell patents for the development and commercialization of stem cell-based…

12th November 2008
The Wisconsin Academy, along with the University of Wisconsin–Madison and the Wisconsin Alumni Research Foundation (WARF), will host a free, two-day event on Nov. 18-19 to highlight the…

6th November 2008
Ten years ago today (Nov. 6, 1998), the publication in the journal Science of a short paper entitled “Embryonic Stem Cell Lines Derived from Human Blastocysts” rocked biology – and the world – as the…

5th November 2008
The Wisconsin Academy, along with UW-Madison and the Wisconsin Alumni Research Foundation (WARF), will host a free, two-day event to highlight the accomplishments of stem cell research in the state…

16th September 2008
Using adult stem cells from bone marrow as “Trojan horses” to deliver a nurturing growth factor to atrophied muscles, Wisconsin scientists have successfully slowed the progression of ALS in rats.

10th September 2008
An opportunity to meet stem cell experts from around the world, unique networking opportunities and a public day of outreach await those attending the World Stem Cell Summit and related events Sunday…

21st August 2008
The WiCell Research Institute, a private, not-for-profit supporting organization to the University of Wisconsin-Madison, is launching its own stem cell bank to distribute cell lines beyond the 21…

13th August 2008
The Stem Cell and Regenerative Medicine Center and the WiCell Research Institute will help supplement World Stem Cell Summit registrations for a limited number of faculty, staff, students and…

4th August 2008
Although scientists have had access to human embryonic stem cells for a decade, precisely how the all-purpose cell gives rise to all other cells in the body and why others do not remains a…

5th June 2008
When forming attitudes about embryonic stem cell research, people are influenced by a number of things. But understanding science plays a negligible role for many people, according to a recent UW-…

8th May 2008
Timothy Kamp, a professor of medicine and physiology at the University of Wisconsin School of Medicine and Public Health, has been awarded the inaugural Schuster Prize for excellence in advancing…

8th May 2008
Invitrogen Corp. and the Wisconsin Alumni Research Foundation announced today (May 8) that they have signed a license for human embryonic stem cell (hESC) patents for the development of research…

2nd May 2008
Stem cell scientist James Thomson has been named one of Time magazine’s “World’s Most Influential People,” with Shinya Yamanaka of Kyoto University. Last year, they each discovered a way to give…

29th April 2008
Pioneering University of Wisconsin-Madison stem cell scientist James Thomson was elected today (April 29) to the National Academy of Sciences.

11th April 2008
A cadre of North America’s leading stem cell scientists will land in Madison April 16 for the third annual Wisconsin Stem Cell Symposium.

9th April 2008
Erik Forsberg has been named to the newly created position of executive director of the WiCell Research Institute. In this position, Forsberg will direct all operations of the private, non-profit…

2nd April 2008
Peter D. Kiernan, III, chair of the Christopher and Dana Reeve Foundation, will provide the keynote address at the World Stem Cell Summit Sept. 22-23, 2008, at the Alliant Energy Center in Madison.

24th March 2008
The UW scientist who first brought stem cells into the scientific spotlight — a discovery that sparked a volatile debate of political and medical ethics — doesn’t seek fame for himself. So when…

12th March 2008
Researchers, business representatives, philanthropists, bioethicists and educators from around the world will be invited to Madison for the World Stem Cell Summit at the Alliant Energy Center on Sept…

9th January 2008
BioTime, Inc. (OTCBB: BTIM) has signed a licensing agreement with the Wisconsin Alumni Research Foundation (WARF) for 173 patents and patent applications relating to human embryonic stem cell…

6th December 2007
For the first time, scientists have used human embryonic stem cells to predict the toxic effects of drugs and provide chemical clues to diagnosing disease.

20th November 2007
When University of Wisconsin-Madison researchers succeeded in reprogramming skin cells to behave like embryonic stem cells, they also began to redefine the political and ethical dynamics of the stem-…

20th November 2007
In a paper to be published Nov. 22 in the online edition of the journal Science, a team of University of Wisconsin-Madison researchers reports the genetic reprogramming of human skin cells to create…

20th September 2007
With the help of a $7.2 million grant from the National Institutes of Health (NIH), a team of University of Wisconsin-Madison researchers will explore the potential of stem cells and natural growth…

7th September 2007
The National Stem Cell Bank has announced that it has received select human embryonic stem cell lines from Novocell, a leading stem cell engineering company based in San Diego. With the addition of…

1st August 2007
In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown…

17th May 2007
In an effort to strengthen and sustain its leadership in the companion fields of stem cell research and regenerative medicine, the University of Wisconsin-Madison will establish a new Stem Cell and…

14th May 2007
Governor Jim Doyle today (May 14) gave a $1 million boost to a University of Wisconsin-Madison spin-off company during a visit to the campus lab that gave birth to its technology.

9th May 2007
Ian Wilmut, the famed Scottish biologist who created Dolly the cloned sheep, is coming to Madison and will give a public lecture on Thursday, May 17, at the Overture Center.

9th April 2007
The interface among molecular biology, medical applications, law, religion and ethics will be the focus of the sixth annual international Bioethics Forum, hosted by Promega Corp.’s BioPharmaceutical…

9th April 2007
Several of the world’s leading experts on the formation of blood and heart cells from stem cells, and clinical applications of stem cells in blood and heart diseases, will come together on Wednesday…

28th March 2007
For the millions of Americans whose vision is slowly ebbing due to degenerative diseases of the eye, the lowly neural progenitor cell may be riding to the rescue.

12th March 2007
The University of Wisconsin School of Medicine and Public Health is among the first medical centers in the country taking part in a novel clinical trial investigating if a subject’s own stem cells…

22nd February 2007
Public policy issues related to human embryonic stem cell research will be the topic of a half-day symposium co-sponsored by the Robert M. La Follette School of Public Affairs at the University of…

 Stem cells used to create critical brain barrier in lab

20th December 2006
Using neural stem cells derived from the fetal brains of rats, a team of Wisconsin scientists has devised a rudimentary blood-brain barrier in the lab.

3rd October 2006
Southeastern Wisconsin residents will have a unique opportunity on Oct. 10 to hear about the promises and limitations of stem cell research directly from the Wisconsin professors and researchers…

3rd October 2006

Three distinguished University of Wisconsin-Madison scientists will meet with corporate chief executives who graduated from the university to brief them on the business applications and marketability…


20th September 2006
Uihlein Wilson Architects of Milwaukee, together with Ballinger of Philadelphia, will design the Wisconsin Institute for Discovery and the Morgridge Institute for Research on the University of…

19th September 2006
The National Stem Cell Bank has expanded its offering of human embryonic stem cell lines to include cells from the University of California, San Francisco (UCSF), it announced today (Sept. 19). With…

18th May 2006
A biochemist at the University of Wisconsin-Madison is one of two recipients of the 2006 Shaw Scientist Award. Designed to help young scientists explore novel research directions, the $200,000 prize…

1st May 2006
A grant program aimed at stimulating collaborative research projects to be included in the Wisconsin Institutes for Discovery has begun with an open invitation to University of Wisconsin-Madison…

14th April 2006
Two of biology’s hottest and most contentious realms will come under the microscope next week at two conferences hosted by Promega Corp.’s BioPharmaceutical Technology Center Institute in Fitchburg.

6th April 2006
Following Monday’s blockbuster announcement of a $150 million public-private investment in the Wisconsin Institutes for Discovery, the University of Wisconsin-Madison will have considerable momentum…

3rd April 2006
The largest individual gift ever to benefit UW-Madison – $50 million from alumni John and Tashia Morgridge – will pave the way for pioneering scientific collaboration at the Wisconsin Institutes for…

6th March 2006
Liquid crystals, the same phase-shifting materials used to display information on cell phones, monitors and other electronic equipment, can also be used to report in real time on the differentiation…

1st January 2006
Scientists working at the WiCell Research Institute, a private laboratory affiliated with UW-Madison, have developed a precisely defined stem cell culture system free of animal cells and used it to…

20th December 2005
Working with heart attack-stricken mice, a team of UW-Madison scientists has shown that embryonic stem cells may one day live up to their clinical promise.

15th December 2005
One of the great challenges for treating Parkinson’s diseases and other neurodegenerative disorders is getting medicine to the right place in the brain. UW-Madison neuroscientist Clive Svendsen and…

12th December 2005
Working with mice, University of Wisconsin-Madison researchers have developed the basis for a therapeutic strategy that could provide hope for children afflicted with Krabbe’s disease, a fatal…

4th November 2005
Gov. Jim Doyle’s veto Thursday (Nov. 3) of Assembly Bill 499 was an important step to preserve Wisconsin’s leadership in the burgeoning field of embryonic stem cell research. The bill would have…

3rd October 2005
The WiCell Research Institute has been selected by the National Institutes of Health (NIH) to establish the federal government’s first and only National Stem Cell Bank (NSCB), it was announced today…

30th September 2005
The National Science Foundation has awarded the UW-Madison Materials Research Science and Engineering Center (MRSEC) nearly $14.8 million over the next six years to continue its leading-edge research…

28th September 2005
The failure of the Wisconsin State Senate to amend Assembly Bill 499, which effectively criminalizes a promising area of biomedical research, sends a frightening message to Wisconsin’s research…

10th August 2005
In an effort to develop new techniques to repair and protect the nervous system in multiple sclerosis patients, including the use of human stem cells, the National Multiple Sclerosis Society has…

26th April 2005
Capitalizing on its across-the-board-strengths in stem cell research, UW-Madison will add two new stem cell programs to its portfolio.

19th April 2005
Unveiling a delivery method that may one day help surgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at UW-Madison have inserted engineered human…

17th February 2005
Tackling a pressing and controversial technical barrier in stem cell biology, scientists at the WiCell Research Institute and UW-Madison have crafted a recipe that allows researchers to grow human…

3rd February 2005
A multidisciplinary team led by James Thomson has received a $1.25 million grant for stem cell research from the W.M. Keck Foundation of Los Angeles.

31st January 2005
After years of trial and error, scientists have coaxed human embryonic stem cells to become spinal motor neurons, critical nervous system pathways that relay messages from the brain to the rest of…

20th November 2004
Wisconsin Gov. Jim Doyle, taking a swing at keeping Wisconsin competitive in the superheated world of biomedical research, announced today (Nov. 17) that over the next several years Wisconsin would…

16th April 2004
To gather a burgeoning number of stem cell researchers into a cohesive community and leverage new resources, UW-Madison has established the new Wisconsin Stem Cell Research Program.

18th February 2004
Human neural stem cells, exposed in a lab dish to the steroid DHEA, exhibit a remarkable uptick in growth rates, suggesting that the hormone may play a role in helping the brain produce new cells,…

22nd December 2003
A team from the Wisconsin National Primate Research Center has taken some of the first critical steps to putting stem cells to use to understand early development and maternal and fetal health.

13th October 2003
James Thomson, the UW-Madison scientist who was the first to isolate and culture human embryonic stem cells five years ago, has been named the recipient of the 2003 Frank Annunzio Award from the…

29th September 2003
The WiCell Research Institute, a non-profit subsidiary of the Wisconsin Alumni Research Foundation, has been named as one of three Exploratory Centers for Human Embryonic Stem Cell Research in the…

28th July 2003
By studying embryonic stem cells from a mouse, researchers at UW-Madison have identified a potential model system for elucidating the stages of normal pancreatic development, as well as for…

26th June 2003
Researchers at the UW Medical School have published what is believed to be the first evidence that human embryonic stem cells can grow into the three major types of muscle cells found in the heart….

9th June 2003
Scientists working with cells that may someday be used to replace diseased or damaged cells in the brain have taken neural stem cell technology a key step closer to the clinic.

10th February 2003
The technique that helped revolutionize modern biology by making the mouse a crucible of genetic manipulation and a window to human disease has been extended to human embryonic stem (ES) cells.

26th April 2002
The Wisconsin Alumni Research Foundation has signed two licensing agreements allowing a company and another university to distribute human embryonic stem cells in research.

30th January 2002
Using stem cells as a window to the earliest developmental processes in the human brain, scientists have found that a group of genes critical for brain development is selectively disrupted in Down…

9th January 2002
The Wisconsin Alumni Research Foundation and Geron Corporation today announced an agreement for the commercialization of human embryonic stem cell technology.

30th November 2001
In a set of meticulous experiments, scientists have demonstrated the ability of human embryonic stem cells to develop into nascent brain cells and, seeded into the intact brains of baby mice, further…

19th November 2001
A portion of the funds received by the State of Wisconsin in a price-fixing settlement with vitamin manufacturers has been directed toward stem cell research at UW-Madison.

5th September 2001
The National Institutes of Health and the WiCell Research Institute, Inc., of Madison announced today, Sept. 5, the signing of a Memorandum of Understanding for research use of WiCell’s existing five…

4th September 2001
For the first time, scientists have demonstrated that undifferentiated human embryonic stem cells can be teased down a developmental pathway to become blood cells.

1st February 2000
In an effort to move human embryonic stem cell technology into the mainstream of academic and corporate research, the Wisconsin Alumni Research Foundation has established a private subsidiary whose…

6th November 1998
The dream of one day being able to grow in the laboratory an unlimited amount of human tissues for transplantation is one step closer to reality.