Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Transcriptional responses to anticancer drugs in iPSC-derived heterogeneous cardiac cell cultures Abstract: Doxorubicin (DOX) and 5-fluorouracil (5-FU) are commonly prescribed to treat a variety of cancers. Though efficacious, up to 48% of patients treated …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Above the genome: post-transcriptional mechanisms that guide stem cell biology Abstract: The enormous scientific and therapeutic power of stem cells lies in their remarkable ability to give rise to diverse, functionally mature cells through …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Metabolic Modulation to Minimize Graft-versus-host Disease and Promote Anti-cancer Immunity Abstract: Metabolic reprogramming represents a dynamic process during the evolution of in vivo T cell responses. In the presented studies, I will highlight the …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: ISSCR Initiatives & Resources: Supporting the Global Stem Cell Research Community ISSCR Website Our Seminar Lab Series will be offered in hybrid format: The in-person seminar is each Tuesday during the semester from noon-1 p.m. …
Discovery Building, Orchard View @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Girk3 in bone development and disease Abstract: Musculoskeletal issues are among the top reasons that patients visit their doctors in the United States, particularly with aging. Despite their prevalence, there are still significant treatment gaps …
Health Sciences Learning Center, Rm 1345 @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Inducible Expression of MKK3 as a Potential Therapeutic to Increase Skeletal Muscle Mass Abstract: Mechanical stimuli play a major role in the regulation of skeletal muscle mass and the maintenance of muscle mass significantly …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: The spatio-temporal regulation of neural stem cells by their progeny Abstract: Life-long maintenance of stem cells implies that feedback mechanisms from the niche regulate their quiescence/activation dynamics. Using mouse adult subventricular neural stem cell …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: The machinery of innate heart regeneration Abstract: The human heart has minimal capacity to regenerate new muscle after a cardiac injury and is a key target for innovations in regenerative medicine. Here I will …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Integrin α4-dependent Interaction with the Niche During Development Programs Hematopoietic Stem and Progenitor Cells Abstract: Hematopoietic stem and progenitor cells (HSPCs) reside in a microenvironment that regulates their behavior by interactions with niche support …
Discovery Building, DeLuca Forum @ 12:00 pm
https://stemcells.wisc.edu/stem-cell-seminar-lab-series/
Title: Unique metabolic demands of the germline stem cell lineage: glycolysis is required for stem cell maintenance and egg chamber growth, but not mitotic proliferation, meiotic entry, nor oocyte specification Abstract: Stem cells and their …