Susan L. Thibeault, PHD, CCC-SLP
Position title: Professor, Surgery / Biomedicial Engineering / Communicative Sciences and Disorders
My research program focuses on tissue engineering the extracellular matrix of the vocal fold lamina propria. To this end, my lab utilizes adult stem cells in addition to immortalized vocal fold fibroblast lines that we have developed. My lab group studies the interaction of varying cells to different synthetic hydrogels. We are also investigating the effects of mechanical forces on cell differentiation. Vocal folds undergo extreme variations in mechanical forces. We plan to compare the effects of different cells to such mechanical forces to see if cells change their differentiation.
- Palencia L, Das A, Palecek SP, Thibeault SL, Leydon C. Epidermal growth factor mediated healing in stem cell-derived vocal fold mucosa. J Surg Res. 2015 Jul;197(1):32-8, PMC4457682.
- Lungova, V., Leydon, C., Thibeault, SL. Derivation of epithelial cells from embryonic stem cells as an in vitro model of vocal mucosa. Methods Mol Biol. 2016;1307:237-43. PMID25403465
- Fishman JM, Long J, Gugatschka M, DeCoppi P, Hirano S, Hertegard S, Thibeault SL, Birchall MA. Stem cell approaches for vocal fold regeneration. Laryngoscope. 2016 Aug;126(8):1865-70, PMID26774977.
- Woo JH, King SN, Hoffman H, Dailey S, Wang S, Christensen MB, Thibeault SL. MERS versus Standard Surgical Approaches for Porcine Vocal Fold Scarring with Adipose Stem Cell Constructs. Otolaryngology Head Neck Surgery. 2016 Oct;155(4):612-23. PMID 27165681