Zachary T. Campbell, PhD

Position title: Visiting Associate Professor, Department of Anesthesiology


Website: Website

Phone: 608-265-6710

Organ System/Disease Focus:
Aligned Research Focus:
Basic stem cell science



Research Description: 

We are interested in how plasticity in neurons that detect and amplify pain signals occurs. We make use of murine and human nociceptor models to better understand conserved processes that contribute to chronic pain – a pervasive and devastating condition.

Selected References: 

1. Chase R, de la Peña JB, Smith PR, Lawson J, Lou TF, Stanowick AD, Black BJ, Campbell ZT. Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain. FASEB J. 2022 36(7): e22422

2. Smith PR, Loerch S, Kunder N, Stanowish AD, Lou TZ, Campbell ZT. Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance in sensory neurons. Doi: 10.1038/s41467-021-27160-4. Nature Communications. 2021. 12 (1): 1-16

3. de la Peña JB, Kunder N, Lou TZ, Chase R, Stanowick S, Barragan-Iglesias P, Pancrazio JJ, Campbell ZT. A role for translational regulation by S6 kinase and a downstream target in inflammatory pain. British Journal of Pharmacology. 2021. 178: 4675–4690

4. de la Peña JB, Barragan-Iglesias P, Lou TC, Loerch S, Kunder N, Shukla T, Song J, Megat S, Moy JK, Wanghzou A, Ray PR, Hoyt K, Steward O, Price TJ, Shepherd J, Campbell ZT. Intercellular Arc signaling regulates vasodilation. J Neuroscience. 2021. 37: 7712-7726

5. Barragán-Iglesias P, Lou TF, Bhat V, Megat S, Burton M, Price T, Campbell ZT*. Inhibition of Poly(A)-Binding Protein with an RNA mimic reduces pain sensitization in mice. Nature Communications 2018. 9(1):10