Post-doctoral Scholar
Genetics of Metabolism, Department of Biochemistry
Position Description: We are looking for a post-doctoral scholar who will help us to harvest the genetic clues from our genetic screen. The scholar will be able to identify novel genes and pathways and develop a research program that shows how these genes and pathways modulate diet responsiveness.
Project Description: The response to diet is highly variable across individuals. We have on ongoing genetic screen to discover the genetic drivers of metabolic flux in response to diet. We have placed genetically diverse outbred mice on two extreme diets (low-fat/high-carb and high-fat/low-carb). In collaboration with Richard Kibbey’s lab at Yale, we are using stable isotope tracers to measure metabolic flux through multiple pathways. Using quantitative genetics, we are mapping metabolic flux to DNA markers in the genome to discover the genetic drivers of metabolic flux. This work will help to understand the genetic basis for differences in response to particular diets and hopefully will identify molecular markers that predict diet outcome, a step towards customized nutrition.
Start Date: 2022
Contact:
Alan D. Attie, Ph.D.
Jack Gorski Professor of Biochemistry, University of Wisconsin-Madison
Email: adattie@wisc.edu
Web site: https://biochem.wisc.edu/faculty/attie
Research Associate (Postdoctoral)
Medicine (Hematology/Oncology)
Project: A Postdoctoral Research Fellow position is available for translational development of Mesenchymal Stromal Cells (MSC) for regenerative medicine
Group Leader: Jacques Galipeau, MD
Requirements: Candidates must have a Ph.D. degree or equivalent in a relevant area of biomedical sciences and evidence of past productivity. The candidate should have experience working with tissue culture of cell lines and primary cell lines and have basic skills in biochemistry and molecular biology, as well as willingness to learn new techniques. Experience with flow cytometry and willingness to work with murine animal models of human disease is desired.
Job Duties: A Postdoctoral Research Fellow position is available for development and engineering of second generation mesenchymal stromal cells (MSCs) for cancer and immune disorders under Group Leader, Jacques Galipeau, MD. The Galipeau group is located in state-of-the-art laboratory space at the University of Wisconsin School of Medicine and Public Health and UW Carbone Cancer Center. The Galipeau group is internationally recognized for its MSC work and seeks to add a postdoctoral Fellow to its research program examining MSCs in inflammatory disorders and tissue regeneration. The successful applicant will lead a mentored pre-clinical research project with potential for direct clinical translation. The candidate will develop and study the physiology and translational use of mesenchymal stromal cells for cell therapy applications in immune disorders and tissue injury syndromes. The candidate will also be expected to contribute to the preparation of manuscript and reports and to regularly present their findings at meetings, lab meetings and national/international symposia. Candidates must have a Ph.D. degree or equivalent in a relevant area of biomedical sciences and evidence past productivity. Please submit your CV and name/contact information of three individuals that can provide academic references.
Start Date: 2022 (open posting)
Percent Time: 100%
Salary: NIH Scale
Contact: Jacques Galipeau, MD: jgalipeau@wisc.edu
Research Associate (Postdoctoral)
Medicine (Hematology/Oncology)
Requirements: Candidates must have a Ph.D. degree or equivalent in a relevant area of biomedical sciences and evidence of past productivity. The candidate should have experience working with tissue culture of cell lines and primary cell lines and have basic skills in biochemistry and molecular biology, as well as willingness to learn new techniques. Experience with flow cytometry and willingness to work with murine animal models of human disease is desired.
Job Duties: A Postdoctoral Research Fellow position is available for development and engineering of immune effector cells with synthetic cytokines for cancer and immune disorders under Group Leader, Jacques Galipeau, MD. The Galipeau group is located in state-of-the-art laboratory space at the University of Wisconsin School of Medicine and Public Health and UW Carbone Cancer Center. The group is internationally recognized for its work on mesenchymal stromal cells, engineered fusion cytokines for cancer therapy and for neuroinflammatory disease and seeks to add a postdoctoral Fellow to its research program. The successful applicant will lead a mentored pre-clinical research project with potential for direct clinical translation. The candidate will develop and study the physiology and translational use of novel engineered fusokines for therapy applications in cancer, inflammatory bowel disease and neuro-immune disorders. The candidate will also be expected to contribute to the preparation of manuscript and reports and to regularly present their findings at meetings, lab meetings and national/international symposia. Please submit your CV and name/contact information of three individuals that can provide academic references.
Start Date: 2022 (open posting)
Percent Time: 100%
Salary: NIH Scale
Contact: Jacques Galipeau, MD: jgalipeau@wisc.edu