Thaddeus G. Golos, Director
Projects to develop cell replacement therapies may require that researchers implant stem cells into nonhuman primates to test efficacy and assess possible side effects before proceeding to human trials. In this context, nonhuman primates will be made available through the Nonhuman Primate Services core at the Wisconsin National Primate Research Center. Specific services include the provision of appropriate monkeys and primate tissue for projects, specialized animal husbandry, assistance with procedures such as surgeries and clinical assessments of monkeys, and appropriate terminal procedures and preparation of tissues for analysis.
As a part of nonhuman primate services, Precision Medicine Precision Core Therapies Subunit at WNPRC directed by Igor Slukvin provides the MHC-defined preclinical model for novel hematopoietic stem cell therapies. Bone marrow transplantation core assists researchers in isolation and genetic modification/editing of hematopoietic stem cells, animal conditioning, bone marrow transplantation, and assessment of bone marrow engraftment.