Dr. Liu obtained his medical degree from Capital Medical University and residency training in Internal Medicine in Peking Union Medical College Hospital in Beijing, China. He earned his PhD in from the University of Texas M.D. Anderson Cancer Center, and he did his postdoc training in the University of Michigan. Dr. Paul Liu is a tenured Senior Investigator and the Head of the Oncogenesis and Development Section in the National Human Genome Research Institute, NIH, in Bethesda, MD. Dr. Liu’s laboratory investigates the molecular mechanisms of leukemia, especially for those involving CBFB and RUNX1. Dr. Liu cloned the breakpoints of chromosome 16 inversion, a common chromosome abnormality in acute myeloid leukemia, and identified the molecular consequence of the inversion as the generation of a fusion gene, CBFB-MYH11. Dr. Liu’s lab uses genetic and genomic approaches, as well as mouse, zebrafish, and human iPSC models for their research. More recently, Dr. Liu established a natural history study of patients with a genetic disease called familial platelet disorder (FPD), which is caused by germline mutations in RUNX1. The first such study of this disease, Dr. Liu and his team are following the largest cohort of FPD patients in the world, performing deep phenotyping and extensive genomic studies to understand the mechanisms of disease progression. In addition to running his own lab, Dr. Liu plays active leadership roles at NHGRI and NIH, serving as the Deputy Scientific Director of NHGRI, and as members on many key committees. Dr. Liu has published over 160 papers, and he has been recognized by several awards. He is an elected member of American Society of Clinical Investigation and Association of American Physicians, and he is an elected fellow of the American Association for the Advancement of Science (AAAS).
Our Seminar Lab Series will be offered in hybrid format:
The in-person seminar is each Tuesday during the semester from noon-1 p.m. at the Wisconsin Institute for Discovery, DeLuca Forum.
To join online, please click the zoom link below:
https://uwmadison.zoom.us/j/96958883460
*if you are asked for a passcode: 936743