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Matthew E. Brown, Assistant Professor, Surgery, “Immunogenicity of PSC Therapies”

April 21, 2020 @ 12:00 pm - 1:00 pm

The UW Stem Cell & Regenerative Medicine Center will continue to offer its weekly seminar, but we will transition to ONLINE only. We will be offering this live (synchronously), so you can participate in the Q & A session in real time.

To connect and join our live Tuesday Stem Cell Seminar Series (now online), please click on this public link: https://us.bbcollab.com/guest/ecfe2a1900ab4a6ca9bd6b20e4b7bb07

We do encourage you all to review the instructions, linked below, in order to orient yourselves to this environment. You are also welcome to jump into the room and test your ability to connect, including turning on your audio and video. Our center’s Administrator, Hollie, will be in the room starting at 10:30 AM CT and can offer assistance as time allows.

Guest Access Instructional Overview: https://go.wisc.edu/ftti09

If you have any questions, please contact Hollie: hjthomps@medicine.wisc.edu

**STUDENTS: If you are a current student, an announcement has been posted to your Canvas course with instructions on how to access the course. IF you have issues getting into Canvas, please use guest link and let Hollie know via email.

Immunogenicity of PSC Therapies

Matthew E. Brown, Assistant Professor, Surgery | Director, Humanized Mouse Core | Division of Transplantation

The Brown Laboratory in the UW-Madison Department of Surgery/Transplantation Division focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. Lab members are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized mouse models, the goals are to 1) improve traditional organ transplantation outcomes, 2) gain new insights into PSC biology and immunology, and 3) enable curative regenerative medicine therapies. This presentation will explore the use of humanized mouse models, including the NeoThy model, in the context of PSC transplantation immunology and virology studies, and give an overview of the Brown lab’s investigations into the immune response to PSC-based cardiovascular therapies.



April 21, 2020
12:00 pm - 1:00 pm
Event Category:


Stem Cell & Regenerative Medicine Center


Wisconsin Institutes for Discovery (WID)
330 N. Orchard St.
Madison, WI 53706 United States
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