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Jacques Galipeau, Professor, Medicine, ” Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities”
September 25 @ 12:00 pm - 1:00 pm
Topic: Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
Abstract: Mesenchymal stromal cells (MSCs) have been the subject of clinical trials for more than a generation, and the outcomes of advanced clinical trials have fallen short of expectations raised by encouraging pre-clinical animal data in a wide array of disease models. In this presentation, important biological and pharmacological disparities in murine pre-clinical research and human translational studies are highlighted, and analyses of clinical trial failures and recent successes provide a rational pathway to MSC regulatory approval and deployment for disorders with unmet medical needs.