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Dr. Yunlong Tao, Research Associate – Dr. Zhang’s Stem Cell Research Laboratory, “Cell Therapy for Parkinson’s Disease – Preclinical Studies in Rodents and Non-human Primates”

January 26 @ 12:00 pm - 1:00 pm

SCRMC Seminar Lab Series, ONLINE Tuesday, Jan 26TH 2021 @ 12PM CT; Dr. Yunlong Tao Assistant Scientist Dr. Zhang’s Stem Cell Research Laboratory presents, "Cell Therapy for Parkinson’s Disease – Preclinical Studies in Rodents and Non-human Primates"

CONNECTION INFO
The UW Stem Cell & Regenerative Medicine Center will continue to offer its weekly seminar online in a live (synchronously) format, so that you, as all can continue to participate in the Q & A session in real time.

To connect and join our live Tuesday Stem Cell Seminar Series (now online), please click on this public link (be sure to allow mic / video access when prompted in browser): https://us.bbcollab.com/guest/872ec396918e4a2c825824e04f21bd01

We do encourage you all to review the instructions, linked below, in order to orient yourselves to this online platform environment. You are also welcome to jump into the room and test your ability to connect, including turning on your audio and video, prior to the scheduled event time. Our center’s Administrator, Hollie, will be in the room starting at 11:00 AM CT  the day of and can offer assistance as time allows.

Guest Access Instructional Overview: link coming soon

If you have any questions, please contact Hollie: hjthomps@medicine.wisc.edu

**STUDENTS: If you are a current student, please join the course room via the BBCollaborate option in your Canvas course portal.

 


TOPIC

Cell Therapy for Parkinson’s Disease – Preclinical Studies in Rodents and Non-human Primates

SPEAKER

Dr. Yunlong Tao
Assistant Scientist
Dr. Zhang’s Stem Cell Research Laboratory

ABSTRACT
Degeneration of dopamine (DA) neurons in the midbrain underlies the pathogenesis of Parkinson’s disease (PD). Supplement of DA via L-Dopa alleviates motor symptoms but does not prevent the progressive loss of DA neurons. A large body of experimental studies, including those in nonhuman primates, demonstrates that transplantation of fetal mesencephalic tissues improves motor symptoms in animals, which culminated in open-label and double-blinded clinical trials of fetal tissue transplantation for PD. Unfortunately, the outcomes are mixed, primarily due to the undefined and unstandardized donor tissues. Generation of induced pluripotent stem cells (iPSCs) enables standardized and unlimited cell source for PD. In this talk, I will present our pre-clinical studies using stem cell derived DA neurons in rodent and non-human primate PD models to evaluate the cell therapy for PD.

Details

Date:
January 26
Time:
12:00 pm - 1:00 pm
Event Category: