Dr. Michael Moore, Ph.D., Professor of Biomedical Engineering, Tulane University, “Microphysiological Models of the Nervous System: Beyond the Brain”
March 2 @ 12:00 pm - 1:00 pm
The UW Stem Cell & Regenerative Medicine Center will continue to offer its weekly seminar online in a live (synchronously) format, so that you, as all can continue to participate in the Q & A session in real time.
To connect and join our live Tuesday Stem Cell Seminar Series (now online), please click on this public link (be sure to allow mic / video access when prompted in browser): https://us.bbcollab.com/guest/872ec396918e4a2c825824e04f21bd01
We do encourage you all to review the instructions, linked below, in order to orient yourselves to this online platform environment. You are also welcome to jump into the room and test your ability to connect, including turning on your audio and video, prior to the scheduled event time. Our center’s Administrator, Hollie, will be in the room starting at 11:00 AM CT the day of and can offer assistance as time allows.
If you have any questions, please contact Hollie: email@example.com
**STUDENTS: If you are a current student, please join the course room via the BBCollaborate option in your Canvas course portal.
Microphysiological Models of the Nervous System: Beyond the Brain
Dr. Michael Moore, Ph.D.
Professor of Biomedical Engineering
Use of 3D microscale engineered tissues as high-content assays for drug screening during preclinical drug development has rapidly been gaining ground, with the hope of curbing attrition rates and rising costs. While many brain-on-a-chip and brain organoid models have been described, there has been comparatively little development of such models of the peripheral nervous system. In this presentation, I will give a brief overview of microphysiological models of the nervous system, and then describe our laboratory’s efforts to develop models of peripheral nerve. We have shown how a unique 3D model of peripheral nerve may recapitulate many aspects of nerve physiology and pathology. We are now progressing toward a model of synaptic communication between peripheral nerve and the spinal cord, which we are developing in response to our nation’s crisis of opioid overuse and addiction. Finally, I will provide some perspective on our lab’s experience with technology commercialization, particularly formation of AxoSim, a startup company that is providing microphysiological models of the nervous system as a service to pharmaceutical companies.