Award-winning Grad Student Research Could Benefit Industry

Three members of UW-Madison Mechanical Engineering Professor, and SCRMC faculty member, Lih-Sheng (Tom) Turng’s research group at the Wisconsin Institute for Discovery won top awards for their exceptional research papers at the Society of Plastics Engineers annual technical conference in Detroit in March 2019.

Man with severe autoimmune disease gets stem cell transplant at UW

SCRMC Faculty member Dr. Peiman Hematti runs the lab involved in a procedure of stem cell transplants for scleroderma (a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases) at UW-Hospital, after a national study last year found it worked better than drugs.

New Technique Enables Versatile 3D Control Over Stem Cell-Derived Organoids

University of Wisconsin-Madison engineering professors, and SCRMC Faculty members, Randolph Ashton and Lih-Sheng “Tom” Turng have partnered on a project to create hydrogel molds that will allow researchers to more precisely control the three-dimensional structures of organoids. They detailed their work in a recent paper in the journal Acta Biomaterialia.

Two professors honored with Shaw Scientist Awards to support innovative research

Assistant professor of neuroscience and SCRMC faculty member, Darcie Moore, is one of two recipients of 2019 Shaw Scientist Awards from the Greater Milwaukee Foundation. Moore is studying adult stems cells in an area of the brain important for learning and memory. A decrease in these cells over time is associated with cognitive decline, so Moore is exploring how stress and aging change the process by which the cells divide.

A new way to wind the development clock of cardiac muscle cells

These days, scientists can collect a few skin or blood cells, wipe out their identities, and reprogram them to become virtually any other kind of cell in the human body, from neurons to heart cells.

The journey from skin cell to another type of functional cell involves converting them into induced pluripotent stem cells (iPSCs), which are similar to the developmentally immature stem cells found in embryos, and then coaxing them to mature into something different.

‘Bad guy’ fibrocytes could help rebuild damaged tissue

‘Bad guy’ fibrocytes could help rebuild damaged tissue
May 8, 2019 By Susan Lampert Smith

Could a blood cell type responsible for scarring and diseases such as pulmonary fibrosis be repurposed to help engineer healthy tissue?

A new study by a University of Wisconsin School of Medicine and Public Health researcher shows that someday, fibrocytes may be used for regenerative therapies for people who need to have their vocal folds or other tissues rebuilt after damage or loss.

UW–Madison research team finds new ways to generate stem cells more efficiently

Induced pluripotent stem (iPS) cells are among the most important tools in modern biomedical research, leading to new and promising possibilities in precision medicine. To create them requires transforming a cell of one type, such as skin, into something of a blank slate, so it has the potential to become virtually any other kind of cell in the body, useful for regenerative therapies for everything from heart disease to diabetes.

Generating Stem Cells: a Path to Greater Efficiency

SCRMC Faculty member Rupa Sridharan, assistant professor of cell and regenerative biology, studies the epigenetics of cell fate. By examining and manipulating which of a cell’s genes are expressed, she seeks to understand how the cell transitions from one type to another. “We start off with cells that are completely differentiated, meaning they can only do one thing,” explains Sridharan. “For example, a skin cell can only be a barrier, a lung cell can only help us breathe, whereas a pluripotent cell has the potential to become any of those cells.”

Faculty receive WARF, Kellett, Romnes awards

SCRMC Faculty members, Judith Kimble (/Biochemistry) is honored by receiving a WARF-named professorship, and Weibo Cai (Radiology / Medical Physics), is honored with an H.I. Romnes Faculty Fellowship. Congratulations to both of these fine researchers and teachers.